Juvenile myoclonic epilepsy (or JME for short) is a common type of epilepsy that usually begins in teenage years (12-18 years old).

The young person usually has experienced what are known as “myoclonic jerks”, which are sudden, brief muscle contractions affecting mainly the shoulders and arms. They occur soon after waking up in the morning and can cause problems for example while brushing teeth, holding cutlery, or putting on makeup. Often teenageers wrongly assume that the jerks are normal, or caused by nervousness or clumsiness. These seizures can also be triggered by sleep disturbance or lack of sleep, drinking alcohol, fasting, menstruation, or sometimes by flickering lights.

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The young person may also experience a second type of seizure: generalized tonic-clonic seizures. These seizures usually begin with a series of myoclonic jerks, which become more and more severe and spread through the body. The child then has a tonic-clonic seizure. The child may be able to tell from the myoclonic jerks that she is about to have a tonic-clonic seizure, and can lie down in a safe place to avoid injury.

Up to one-third of young people with JME also have absence seizures (blank attacks or vacant staring).

Most people with JME have normal range of IQ, but there are often weaknesses in spoken language and memory. There are some reports that people with JME are more impulsive than others, with effects on their social interactions and career success.

JME is usually treated with a combination of antiepileptic drugs and lifestyle changes. Factors such as tiredness, irregular sleep, drinking alcohol, and missing doses of medication can all trigger seizures. Seizures often continue into middle age but in two-thirds of cases can be well controlled.

There are many things we dont know about JME, including what causes it and how it affects people in different ways. Please join our research study BIOJUME to help us find the answers. We are also looking for young people to help write a booklet to share with others who are newly diagnosed.

Click here to read about our BIOJUME study being featured in Epilepsy Professional Magazine’s Summer 2017 issue

Epilepsy in Children

Many types of epilepsy only occur in childhood, often starting and finishing before 16 years of age. Childhood epilepsies include some of the simplest as well as the most difficult seizure types to treat. Quite often, there are effects on a child’s development and behaviour. Therefore, it is important to be aware of this when considering a child’s epilepsy diagnosis.

Our research studies

Our epilepsy research is aimed at understanding the basic level of cause and mechanism, as well as the clinical level of symptom management.


Biology of Juvenile Myoclonic Epilepsy (BIOJUME)


Changing Agendas on Sleep, Treatment and Learning in Childhood Epilepsy (CASTLE)


mTOR Pathway Diseases